Dr. Baldev Chaddha, a well-qualified fertility expert, runs a fertility clinic and a sperm bank in New Delhi, that guarantees a high quality and specialized sperm for the purpose. Unfortunately, he has more failed cases to his credit than successes. A healthy, high performing donor is the need of the hour. Vicky Arora, a young, good-looking, Punjabi boy from Lajpat Nagar, is the only son and of no financial support to his family. As luck would have it, Dr. Chaddha meets Vicky and concludes that he could be THAT donor he had been looking for. From here on, Chaddha's days and nights are spent in convincing Vicky till he finally gives in. Meanwhile, Vicky finds love in Ashima Roy, a pretty Bengali girl, but soon their romantic world comes crashing down. With a brief emotional roller coaster ride, Vicky Donor is a comedy-drama with a light-hearted take on the subject of sperm donation.