Dhama Chaukdi is the story of four underworld dons - Mani Aiyer from Madras (Mukesh Tiwari), Pappu Yadav from Bihar (Akshay Yadav), Lallan Pyare from UP (Deepak Chauhan) and Sanjay Apte from Aamchi Mumbai (Yadhuveer Yadav) - who are staunch enemies having businesses in Mumbai. They would willingly give one eye if it means blinding the two eyes of the other. But the arrival of a new police commissioner changes everything. Soon, the four find themselves facing a common enemy. Uniting to try out some other business, they fall into the grip of the one-man-show director (Sanjay Mishra) who assures them that he will make them superstars. The four have to shift locales to a village to keep away from the cops, only to be troubled by a smalltime goon whom they can deal with anytime, but at the risk of blowing their cover. The dons become tolerant and Bollywood sensitive with time. On the last day of the shoot, the commissioner makes his appearance. Will these funny foursomes become superstars? Or will their comedic journey put them behind bars?